Annual Global Discovery to Development Innovation Forum Speakers
Jonathan S Mason
Senior Research Fellow
Dr Jonathan S Mason is a Senior Research Fellow at Sosei Heptares for GPCR structure-based drug design and a Scientific Advisor to several innovative biotech companies (US, UK, Japan). He has four decades years of global pharmaceutical drug discovery experience and is an experienced leader and scientific expert for drug design technologies (computational medicinal chemistry / CADD, structural biology, in silico ADME/tox etc). He previously led teams involving computational chemistry and structural biology/chemistry at Lundbeck (Denmark, Divisional Director), Pfizer (UK, Executive Director MISD), Bristol-Myers Squibb (US, Director Structural Biology & Modeling) and Rhône-Poulenc Rorer (now Sanofi) in the UK, France and USA, including an initial 5 years as a medicinal chemist. He completed his PhD at Queen Mary, U. London and become an early pioneer of the use of computational chemistry / CADD approaches in drug discovery research. More recent focus includes enhancing computer-assisted drug design with full binding site water networks and their energetics for potency, selectivity and kinetics and the prediction of binding affinity (FEP).