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Bioprocess Innovation Leaders Summit Speakers

Valentina C. Ciccarone

Director, Gene Expression Strategies

Ph.D. in Cell Biology from Fordham University and Sloan Kettering Cancer Center in New York.Director and Principal Scientist at MacroGenics, Inc. (2002- present). Responsible for the development of stable cell lines for production of engineered, humanized antibodies and multi-specific proteins targeting tumor, auto-immune, and infectious disease markers; Also responsible for transient protein expression in mammalian cells. Section Leader and Principal Scientist at Life Technologies. 1990 - 2002. Responsible for the development of gene delivery and gene expression technologies in eukaryotic cells including Lipofectamine 2000, Bac-to-Bac Baculovirus Expression System and other transfection and expression technologies. Post-doctoral Research Fellow at the National Cancer Institute – Laboratory of Molecular Immunoregulation. 1987-1990. Studied the genetic regulatory elements of the Interferon-gamma gene.